Company intelligence
ATEM Structural Discovery
Cryo-EM for biologics. Decision-ready results, fast.
About ATEM Structural Discovery
ATEM is a specialist cryo-EM CRO working exclusively in biologics development. We answer the specific structural and morphological questions that block pharma and biotech teams from advancing their programs — delivering panel-ready, decision-ready results at the speed development timelines demand. Our work spans three active product areas: * LNP characterization, where AI-enabled morphological analysis translates particle population data into formulation and process development decisions. * High-Throughput 3D Epitope Mapping, where structure determination of antibody-antigen complexes — including membrane protein targets — delivers mechanistic interpretation and actionable design recommendations for antibody engineering and discovery biology teams. * GMP Viral Contamination Testing, where morphological analytical assays under GMP conditions produce regulatory-defensible evidence for IND, BLA, and cell bank qualification submissions. Unlike generalist analytical providers, ATEM scopes every engagement to the question being asked — not the broadest analysis that can be justified. The deliverable is always the same: a clear answer to the client's development question, documented for regulatory or internal use, and interpreted in language the development team can act on directly. To find out more about ATEM, visit www.atem.bio
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Signals from ATEM Structural Discovery
5 published signals
Products & Services
ATEM Structural Discovery developed a machine learning-based algorithm that transforms cryo-EM LNP images into quantitative morphological insights, delivering results within two weeks.
Reported by ATEM Structural Discovery
Research & Knowledge
ATEM Structural Discovery reported a standard deviation of 0.7 nm when repeating the analysis across three operators.
Reported by ATEM Structural Discovery
Research & Knowledge
ATEM Structural Discovery reported a coefficient of variation across three replicates under 1% for repeatability.
Reported by ATEM Structural Discovery
Research & Knowledge
ATEM Structural Discovery reported a 99% confidence interval narrowed to 0.92 nm for particle count and sampling precision around the estimated mean diameter.
Reported by ATEM Structural Discovery
Research & Knowledge
ATEM Structural Discovery reported AI and human annotations agreed on 96.3% of classifications on average for Solid Core particles and Bi-Phasic Dense particles.
Reported by ATEM Structural Discovery