Plowshare Therapies LLC

About Plowshare Therapies LLC

Plowshare Therapies develops durable treatments for severe pediatric rare diseases with urgent unmet medical need. Our initial focus is Maple Syrup Urine Disease, advancing a gene therapy to restore normal metabolism early in life. Our lead program holds FDA Orphan Drug and Rare Pediatric Disease designations, signaling regulatory alignment and progress toward IND readiness. We are developing a therapy built on decades of translational research and clinical experience, pairing modern vector engineering with conservative development choices. Plowshare is mission-locked at formation, ensuring stewardship, accountability, and long-term alignment with patient outcomes. The company emerged from a long history of care within Amish and Mennonite communities, providing deep disease insight and a strong foundation for execution.