Biointron published a study showing structure-guided disulfide engineering restricted Fab movement in human IgG2 to produce meaningful gains in CD40 and 4-1BB agonism.

Public source

Publisher name

Public post

Same Binding, Different Biology: Biasing Antibody Conformation for Productive Receptor Signaling Antibody engineering has traditionally focused heavily on the binding ev…

Log in to read the full post

Company

Biointron

Recombinant Antibody Expression, Delivery in 2 weeks (From Gene Sequence to Purified Antibody)

Industry
Biotechnology Research
Location
Zhoupu Town, Pudong New District, CN
Company size
11–50 employees

About Biointron

About Biointron: Founded in 2012 Certified to ISO 9001:2015 High-technology Enterprises CRO supplier for antibody discovery and expression Founded in 2012 and certified to ISO 9001:2015, Biointron is a CRO specializing in antibody discovery, expression, and optimization for global biotech and pharmaceutical companies. Biointron holds a leading position in the antibody expression industry. From gene sequence to purified antibodies, it only takes 2 weeks. We have delivered tens of thousands of recombinant antibodies for more than 3,000 biotech and pharma companies worldwide. We provide antibody discovery, expression and optimization services, including VHH antibody discovery, single B-cell antibody screening, hybridoma sequencing, antibody humanization, antibody affinity maturation, and RushData (an AI antibody wet lab validation service that provides high-throughput wet lab validation for AI/ML-designed antibody candidates, turning computational predictions into experimentally confirmed data). Additionally, Biointron holds global sublicensing rights for ECACC's CHO-K1. Our CHOK1BN cell line, which is derived from CHO-K1, has been filed in the DMF system with the US FDA. By choosing the CHOK1BN cell line, several partners' projects have entered multicenter international clinical trials successfully. For more information, please visit our official website at www.biointron.com or contact us at info@biointron.com

See more

Latest activity

8 signals

Discover more

Similar public activity from other companies.

Customize signals for your business.

Know everything happening across the B2B world, and act on the company movements that matter to you.

© 2026 SeedOpsCompany intelligence.

SeedOps.