Biomay published a paper discovering that the pH-driven fusion process during TFF-mediated solvent exchange plays a predominant role in shaping mRNA-#LNPs properties.
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This paper discovered that the pH-driven fusion process during TFF-mediated solvent exchange plays a predominant role in shaping mRNA-#LNPs properties by facilitating th…
Company
Biomay
- Industry
- Pharmaceutical Manufacturing
- Location
- Vienna, AT
- Company size
- 51–200 employees
About Biomay
Biomay is a GMP manufacturer for plasmid DNA, mRNA and recombinant proteins. We are both technology focused and quality oriented. Our clients appreciate Biomay’s flexibility and reliability. From gene construction to market supply: Biomay delivers for the success of its clients.
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Research & Knowledge
Biomay evaluated post-thaw quality of mRNA-LNPs formulations without or with 10% sucrose using 10 freeze-thaw cycles in freezers set at -10, -30, or -80 °C.
Research & Knowledge
Biomay published a study showing that Mannose-cholesterol LNPs (MC_LNPs) target GLUT1 for BBB transcytosis and preferential glioblastoma uptake.
Research & Knowledge
Biomay conducted Forced degradation studies (FDSs) to evaluate the effects of temperature, oxidation, hydrolysis, and agitation on mRNA-LNP formulations, revealing hydrolysis-induced degradation of distearoylphosphatidylcholine (DSPC) and rapid oxidation-induced mRNA degradation within LNPs.
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