BioPharmaSpec published a technical bulletin exploring how HCP-MS can complement commercial HCP-ELISA by expanding HCP coverage and enabling the identification and quantitation of individual proteins throughout the purification process and in the final product.

BioPharmaSpec provides structural and physicochemical characterization services from laboratories in the UK, Europe (Germany, Italy and Lithuania) and the US (Malvern, PA). We help our clients characterize their biopharmaceutical products cost effectively and quickly through access to our pioneering mass spectrometry expertise. Our technical services include the structural characterization and physicochemical analysis of recombinant biopharmaceuticals such as biosimilars and biobetters, monoclonal antibodies, Antibody Drug Conjugates (ADCs), blood circulating hormones, peptides, gene therapy products and oligonucleotide therapeutics. Using state-of-the-art Chromatographic and Mass Spectrometric instrumentation and methods, BioPharmaSpec applies expertise built up over 45 years of pioneering research, to assist clients in a number of protein characterization methods including Primary Amino Acid Sequencing, N and C terminal sequencing, Amino Acid Analysis, Peptide Mapping, Disulfide Bridge analysis, Glycan analysis and Higher Order Structure of proteins. Our analytical data helps you choose the best cell clone, provide batch to batch comparisons or perform biosimilar testing for biosimilarity and comparability studies. With BioPharmaSpec's support, solid development decisions can be made based on quality analytical data and experience.