CovalX offers mass spectrometry services for confirming the sequence and integrity of expressed proteins and resolving large biological assemblies.
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Today is World Duchenne Awareness Day. The date, 7/9, stands for the 79 exons of the dystrophin gene, the gene mutated in Duchenne muscular dystrophy (DMD). 🏋♂️ Dystro…
Company
CovalX
Protein Interaction Analytics. The accuracy of mass spectrometry for your biologics project.
- Industry
- Biotechnology Research
- Location
- Zurich, CH
- Company size
- 11–50 employees
About CovalX
CovalX has been established as the leader in characterizing protein interactions by mass spectrometry. Providing Innovative Technologies and Exclusive Services, CovalX has been doing business with world-renowned Universities, therapeutic companies, and most major pharmaceutical companies worldwide for many years. CovalX AG developed a unique protocol for measuring intact protein complexes using MALDI mass spectrometry. CovalX both sells the tools and/or services for High-Mass MALDI protein-protein interaction analysis. The main applications involve: • Epitope mapping (both conformational or linear) • Characterizing aggregates from biotherapeutic drugs • Analyzing antibody-antigen interactions • rapid characterization of any protein complexes (stoichiometry, inhibition, etc) CovalX also has flexibility and provides services for characterizing any large macro molecules such as PEGylated proteins or polymers. CovalX has recently restructured by moving some of its hardware support facilities and US sales and marketing into the US and establishing an official subsidiary in the Boston area.
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Latest activity from CovalX
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Research & Knowledge
CovalX runs intact mass analysis using traditional LC-ESI-MS and proprietary High-Mass MALDI MS instruments to measure large proteins and non-covalent complexes
Research & Knowledge
CovalX published a new study by Bates et al. in the Journal of Immunology from OHSU showing that MR1Nb1 is an alpaca-derived nanobody with 1.6 nM affinity for human MR1 that blocks MR1T cell activation when triggered by M. tuberculosis infection, M. smegmatis supernatant, or deazalumazine.
Customers & Market
CovalX has been the analytical resource behind academic research data and patent filings for 20 years.
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