Denuvo by Irdeto published a blog explaining how Denuvo Anti-Piracy works with Proton-compatible games.

Denuvo by Irdeto is the world leader in gaming security, protecting games on desktop, mobile, and consoles. Denuvo provides core technology and services for game publishers/platforms, independent software developers, e-publishers and video publishers across the globe, enabling binary protection for games and enterprise applications across multiple platforms. Denuvo’s gaming security solutions prevent piracy and expose cheats in competitive multiplayer games, empowering publishers to innovate while also protecting their revenue, the integrity of their game, and the gaming experience. With a rich heritage of security innovation and rapid adaptation to the changing demands of the cyber security space, Irdeto is dedicated to being the security partner to empower a secure world where people can connect with confidence.