Onyx published Inside Onyx using Black Book Market Research LLC’s Payer Interoperability Research as a lens for three priorities: production execution, usable clinical data, and infrastructure that can adapt as mandates evolve.

Onyx is a health data intelligence company helping payers move from data exchange to data intelligence. We help health plans connect healthcare data once and make it usable at scale across compliance, clinical, operational, and financial workflows. Today, Onyx supports 55+ payer organizations, including 25+ state Medicaid programs, representing 55M+ lives across our payer network. Onyx was also ranked #1 overall in Black Book’s 2026 payer interoperability research, leading 11 of 18 key performance indicators. Standards-based data exchange is only the beginning. Health plans need data that is complete, current, trusted, and ready to use across the enterprise. OnyxOS connects those pieces. Our FHIR-native platform enables payers to acquire healthcare data once, normalize and organize it into a longitudinal member record, and reuse that foundation across compliance and operational workflows. From CMS interoperability and electronic prior authorization to digital quality, risk adjustment, care management, and payment integrity, Onyx helps health plans put connected data to work. Built for production scale, Onyx combines deep FHIR expertise, healthcare data infrastructure, AI-powered clinical intelligence, and real-world payer execution. From data exchange to data intelligence. OnyxOS: Acquire once. Reuse everywhere.

Founded 2020