Tengrium published a review in IEEE Transactions on Biomedical Engineering by Guan, Bates, and Zhou that catalogs detection and correction literature with enough taxonomic specificity to be useful as an architectural audit checklist.

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Performance degradation in deployed medical AI is well-documented as a phenomenon and almost universally under-addressed as a systems engineering problem. Guan, Bates, a…

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About Tengrium

Tengrium builds confidential compute infrastructure for organizations that hold health data. The core product, Tengrium Vault, ensures that data is decrypted only inside an attested AWS Nitro Enclave — never visible to operators, including Tengrium. Every inference output carries a cryptographic certificate binding the model hash, data hash, and attestation together. Vault is schema-agnostic: structured clinical records (FHIR R4, HL7, CDA), clinical narrative, medical imaging (DICOM — MRI, CT, PET), genomic and molecular data (WGS, WES, RNA-seq, methylation arrays, proteomics), biomarkers, longitudinal time-series from wearables and monitors, and patient-reported outcomes. Higher-level intelligence products are built on the Vault foundation: a Clinical Intelligence Engine for federated AI diagnostics and predictive analytics, patient-specific Digital Twins for simulation and intervention planning, and a Hybrid Human-AI Harness for clinical workflow orchestration. Tengrium is model-agnostic. Customers deploy their own inference pipelines — disease phenotyping, trajectory prediction, clinical synthesis — inside the attested boundary under custodian-controlled encryption keys.

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